2nd - 4th September 2013, Heriot Watt University, Edinburgh
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Programme
 
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Thursday 13th September

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08.00 Conference  Registration Desk Opens
08.15 - 09.45 SME Showcase
Session Chairs:  Maureen Coleman
  Professor Bill Dawson, Bionet Ltd

Presenters:
Diurnal,
Martin Whitaker
Automaxion,
Stephen Bysouth
AlgiPharma AS,
Arne Dessen
Oxford Pharmascience,
Claire Thompson

Keynote Address:  ‘Linkages and Partnerships’
MRC Technology
, David Tapolczay

Imagen Biotech, Rod Benson
Merlin Powder Characterisation, Elaine H Stone
Arraymed, Kenny Lang
 
08.30 - 10.00 Science Café - Personalised Medicines - Science Fact or Science Fiction?
Chairs:  Professor Gino Martini, King's College London
  Dr Linda Hakes, UCB

09.45 - 10.35

Coffee, Posters and Exhibition
10.35 - 12.10    A choice of 4 parallel sessions:
1.   Bugs and drugs I
 

Session Chair: Dr Woei Ping Cheng, University of Hertfordshire

Bacillus anthracis: how to stop the bad guys from killing us all
Speaker:
Professor Les Baillie, Cardiff University

Novel strategies in infection control. Clostridium difficile: germinate to exterminate
S
peaker: Dr Tony Worthington, Aston University

2 x Short Papers from submitted Abstracts
Oral Drug Delivery to Breastfeeding Infants Using a Modified Nipple Shield
Alexander Edwards

Nanoparticle transport across intestinal epithelial cells: pathway switching through bioconjugation
Robyn Fowler

2.   Medicinal Chemistry I
  Session Chair: Professor Robert Hider, King's College London

Lighting the way for GPCR ligand-receptor Interactions
S
peaker: Dr Barrie Kallam, University of Nottingham

Small-Molecule DNA-Interactive Agents as Alternatives to RNAi or Antisense Technologies: Example of a Novel Potential NF-B Inhibitor
Speaker:
Dr Khondaker Miraz Rahman, King's College London

2 x Short Papers from submitted Abstracts
Synthesis and Evaluation of Anticancer Activity of Thiazolidinone Analogues of Flavone
Sudheer Moorkoth

Synthesis and evaluation of novel 11-substituted cryptolepine analogues with potential as anticancer agents
Venkateswara Rao Gudivaka

3.     What is the future of dissolution testing?
 
Session Chair:  Ken Leiper, Chair, JPAG

Regulatory expectations of presentation of dissolution data
S
peaker: David Darling, MHRA

The role of dissolution in bio-waivers based on the Bio-pharmaceutic Classification System
Speaker:
Dr Henrike Potthast, BfArM

2 x Short Papers from submitted Abstracts
Evaluating Micelle-Water Partition Coefficients to assist Prediction of Skin Permeability
Yasser Shahzad

Photothermal Infrared Microspectroscopy - A Novel Method for the Analysis of Single Particles of Pharmaceutical Materials
Jonathan Moffat

4.      Recent advances in vaccine technology: prophylactic and therapeutic I    
  Session Chair: Barry Moore, Xstalbio

Therapeutic Vaccines for HIV and Cancer
S
peaker: Professor Angus Dalgleish, St George's University of London

Vaccine delivery via microneedles: Innate immune response in human skin
Speaker:
Dr James Birchall, Cardiff University

2 x Short Papers from submitted Abstracts
Effects of Dicetyl Phosphate on Bilosome Characteristics for Oral Vaccine Delivery
Jitinder Singh Wilkhu

The role of liposomal formulation in DNA vaccine biodistribution
Behfar Moghaddam

   
12.10 - 13.25 Lunch, Posters and Exhibition
12.30 - 13.20 APS Annual General Meeting
13.25 - 15.00 A choice of 4 parallel sessions:
1.     Bugs and drugs II
 

Session Chair: Dr Karl Malcolm, University of Belfast

Biofilms on medical devices: strategies for prevention and cure
S
peaker: Dr Colin McCoy, Queen's University Belfast

Topical treatment of Onychomycosis: As Hard as Nails
Speaker:
Professor Marc Brown, MedPharm

2 x Short Papers from submitted Abstracts
Site specific & stable PEGylation of an antimicrobial peptide with a novel reagent
Farzad Ahmad Khayrzad

Iontophoretic hydrogel delivery systems for photodynamic treatment of wound infections
Steven Fallows

2.   Medicinal Chemistry II
  Session Chair: Professor Don Cairns, The Robert Gordon University

Diagnostic inositol probes: flipping chairs
S
peaker: Dr Sally Freeman, University of Manchester

From Bench to Bedside; a treatment for Alzheimer's disease
Speaker:
Professor John Storey, University of Aberdeen

2 x Short Papers from submitted Abstracts
Discovery and Evaluation of (E)-Styrylsulfonyl methylpyridines as Novel Anti-cancer Agents
Tiangong Lu

Improving the quality of treatment for patients with cystinosis
Rosaleen Anderson

3.   Developments in dissolution testing and in-vitro in-vivo correlation
 
Session Chair:  Malcolm Dash, MHRA

Recent advances in dissolution/in-vitro release methodology supporting product development and IV-IVC
S
peaker: James Butler, GlaxoSmithKline

Approaches to IV-IVC development for regulatory success
Speaker:
Dr Terry Shepard, MHRA

2 x Short Papers from submitted Abstracts
FT-Raman investigation of Carbamazepine
Parineeta Banedar

Rapid Identification of Legal Highs using Handheld Raman Spectroscopy
Sulaf Assi

4.      Recent advances in vaccine technology: prophylactic and therapeutic II    
 
Session Chair:  Dr Sudax Murdan, UCL

CaP-PCMC - a versatile way of formulating stable multi-component vaccines
S
peaker: Barry Moore, XstalBio Ltd

Development of Novel Antibody-Inducing Vaccines against Human Malaria
Speaker:
Dr Simon Draper, University of Oxford

2 x Short Papers from submitted Abstracts
"Green vaccines" : development of an oral formulation of a Hepatitis B vaccine
Alberto Berardi

Spray drying and vinyl polymers enhance biological activity and folding reversibility of proteins
Mahmud Mamayusupov

   
15.00 - 15.40 Tea, Posters and Exhibition
15.40 - 17.15 A choice of 4 parallel sessions:
1.   Bacterial resistance: challenges and innovations  
 

Session Chair: Dr Richard Harvey, King's College London

Tackling the need for new antibacterial drugs
S
peaker: Wendy Lawson, Imperial College Healthcare NHS Trust

Antibiotic discovery
Speaker: Professor Anthony Coates, St George's University of London

2 x Short Papers from submitted Abstracts
Biosynthesis of Copper Nanoparticles and its Wound Healing Activity
Josyula Venkata Rao

Protection From Bile: Does Size Matter?
Krishnaa Mahbubani

2.      Drugs from natural sources    
  Session Chair: Professor Michael Heinrich, UCL

Plants to treat tissue necrosis caused by snakebites
S
peaker: Professor Anna K Jäger, University of Copenhagen

Drug Discovery in the Endocannabinoid System: High Hopes for New Medicines
Speaker: Professor Dr Jürg Gertsch
, Institute of Biochemistry and Molecular Medicine

2 x Short Papers from submitted Abstracts
Post-marketing surveillance of some herbal remedies marketed in Egypt: Paediatric preparations
Sawsan El-Masry

Toxicological Risk Assessment of Aristolochia species
Johanna Michl

3.     Developments in dissolution testing and in-vitro in-vivo correlation II  
 
Session Chair:  Ken Leiper, Chair, JPAG

2 x Short Papers from submitted Abstracts
Differential Scanning Calorimetry of Street Samples of Crack Cocaine
Mohammad Zaher Shehab

Preliminary development of PAT methods for Controlled Release pellets coating
Kathryn Bradley

Novel statistical approaches to the development of specifications for MR products
S
peaker: Dr Dave Elder, GlaxoSmithKline

The role and future of dissolution testing within a QBD product development framework
Speaker:
Paul Dickinson, AstraZeneca

Award of the Geoffrey Phillips Analytical Science Award

4.   Development of Age-Appropriate Dose Forms  
  Session Chair: Dr Jenny Walsh, European Paediatric Formulation Initiative

Formulation development for the young and the old: a SWOT analysis
S
peaker: Dr Fang Liu, University of Hertfordshire

Challenges Associated with Developing Medicines for Children; An Industry Perspective
Speaker: Terry Ernest, GlaxoSmithKline

2 x Short Papers from submitted Abstracts
Directly Compressed Orally Disintegrating Tablets for Paediatric Drug Delivery: A Novel Heat-Cool Process Strategy
Ali Al-khattawi

tbc
tbc

   
17.20 - 18.15 Plenary APS Award Lecture - Sponsored by AstraZeneca
Biomaterials for Regenerating Organs and Ultrasensitive Disease Detection
Speaker:
Professor Molly Stevens, Imperial College London
20.00 APS "Black Tie" Dinner